408 cases of chronic superficial gastritis diagnosed by fibergastroscopy and histology were treated with Chinese Herbal Formulas. The symptomatic effective rate was 90.5%, while therapeutic effect proved by gastroscopy and histology was 81.9% and 72.8% respectively. These results compared with the control were statistically significant.
In animal experiment, it is shown that Chinese Herbal Formulas had an evident protective effect to the mucous membrane of rats and guinea pigs. These animals had suffered gastritis and gastric ulcer induced by drugs. The effect of Chinese Herbal Formulas was similar to cimetidin. The pharmaceutical mechanism of Chinese Herbal Formulas proved that it could inhibit the secretion of pepsin. The acute and chronic poisoning test was negative both in vitro and in vivo. With the Chinese Herbal Formulas there were nearly no side effects in this study. Therefore it is a new type of herbs in treatment of chronic superficial gastritis and is different from H2-receptor inhibitor.
Zhong Xi Yi Jie He Za Zhi. 1990 May;10(5):269-71, 259. Chinese.